Can I Take Oxycodone With Ibuprofen

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I just gave my husband 600mg ibuprofen 2 hrs ago. Can I give him the 10 mg oxycodone now or do I have to wait 2 more hours?

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Yes, ibuprofen is a different class of drug and can be taken at the same time, though for better pain control they are often staggered. So if he's prescribed oxycodone every 6 hours, you could give a dose, then 3 hrs later give ibuprofen, 3 hrs later give the oxycodone again...and so on. Just make sure he's not exceeding the max dose per day of oxycodone.

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@Stark,

I just wanted to add a second opinion, in that Oxycodone + Ibuprofen is also available as a combination med that goes by the name of "Combunox". Although I've only ever seen this particular med available in a dose containing 5mgs of Oxycodone + 400mgs of Ibuprofen, and haven't come across any higher strengths being marketed... So I'm not aware of the safety involved if someone were to continuously take more than that together.

The thing about Ibuprofen is that while it doesn't necessarily affect the liver in the same way as Acetaminophen (Tylenol), it does reportedly have a negative effect on the kidneys, which I don't see as much of a compromise at all in the event that your husband may be substituting one med for the other (not insinuating that he is, but thought these facts would be important to know none the less).

So to reiterate what Mary suggested, I agree that Oxycodone + Ibuprofen can be taken together, but doing so at a dose above 5mg/400mg is a little concerning to me; whereas taking them apart from one another in 3 hour intervals (as Mary noted) may be a good idea if at all possible.

Has his doctor made any recommendations on this matter as well?

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3

I just took two 200 mg ibuprofen about an hour and a half ago. Can I take an oxycodone/acetaminophen 5-325 now?

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4

I was told I might have colon poly or something like that. My doctor said to take fiber and to watch my diet, but my left side hurts so bad right now. Can I take the oxycodone-acetaminophen 5-325mg plus ibuprofen 250mg?

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5

I am suffering from a severe toothache. I took ibuprofen 4 hours ago with no relief. Can I take one Oxycodone-Acetaminophen 5/325?

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