Is Oxycodone 10 Mg Stronger Than 10mg Hydrocodone

Bridget Says:

I have been on Norco 10/325 for 7 years for chronic pain and disc problems. Needless to say they quit working. Dr just switched me to Percocet 10. Is this stronger and will it help my pain?

13 Replies

Earliest Newest Votes
David Says:

Hi Bridget,

Sorry to hear about your situation. To answer your question though, YES, the 10mgs of Oxycodone contained in Perocet 10/325 is reported to be more potent than 10mgs of Hydrocodone in Norco 10/325. As to how much stronger it is, answers do vary... but from what I've researched, it's analgesic effects appear to be about 1.5-3x stronger.

Does anyone else find this to be true as well?

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Bridget Says:

Thank you very much for answering my question. I hope it helps my pain. I have a 5 year old to take care of and there are days when I feel like I can't even get out of bed.

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David Says:

Anytime Bridget! I'm happy that I could be of assistance! :)

Having to take care of a 5 year old on top of managing pain does sound like a job for super mom! But I will send my prayers that this medication will also help make life a lot easier on you!

Wishing you the best,

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RickHawaii Says:

Benn on pain meds for some years now. Chronic pain in my c5-c6 disks. My opinion is that hydrocodone (norco) and Oxycodone (Percocet) are the same strenght from miligram to miligram. Supposedly its thought hydrocodne is a lttle weakaer than oxycodone, but my experience is they are damn close. Just depends which ones works better for you.

One thing I want to stress is that if you have not been on either of these drugs for a long time follow your docotrs instructions on doseage exactly. 25 mg of either oxy or hydro is FATAL to someone not using these drugs before, no joke!

Over time you develop tolerence so if you have chronic pain your doseage will go up gradually. But initially lowest dose possible. These come in 5mg, 7.5 my 10mg.

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ohmyachingback1970 Says:

Did they stop working for you when the Norco 10/325 changed from the yellow to white by chance? When all dosages of Norco changed to white there began complaints of less pain relief, or rather pain relief lasted much shorter in time than before. I am convinced that when they changed the color agent is was not the only thing that was changed. It is possible that binding agents were also changed, anything inactive that has made it change how some of us digest the medication and therefore the time it takes for the medication to work in our bodies. I hope the new meds work for you!

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hot rod Says:

Yes oxycodone is stronger works much better

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rick Says:

I have been on narco for 10 yrs, my dr put me on oxycodone 10 6 monts ago. They work better than the narco only because of my tolerance, But if u are not use 2 these drugs be very careful. My borther was put on oxycotin and overdosed. fatal. must be caregul--no joke.

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I just found out recently that I have a 5 mm cyst on my lower spine which is why i though I had a broken or fractured tail bone. I will be returning for another MRI in 5 months to see if its growing but i'm sure it is as the pain is getting excruciating and worse by the month.

I agree, I know form my experience, The yellow "Banana" Norco 10/325 were much more effective than the new white 10/325. They certainly did not just change the color. What ever they did, it reduce the pain releif it used to offer. which is probably why my doctor is moving me from the white Norco 10/325 to the Percocet 10/325. The transition from Hydrocodone to Oxycodone will be a great improvement in pain management.

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Buttercup Says:

Yes it worked better than norco but it also made me sleepy.

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Janny Suer Says:

It is a little stronger. I was on Norco 10 for many many years. A few months ago I was put on the Percocet 10/325. My dr said 1 is equal to 3 Norco. They do help but I shake a lot since I've been taking them. I have multiple disabilities that cause severe constant pain. So now I'm diagnosed as having chronic intractable pain. The only added med that gives me any real effect is when I'm given a steroid injection, I usually get 3 injections at the same time but only every 3 months. So I'm pretty good 2 weeks out of every 3 months. I live in Tx... it's hard to get legitimate meds because of the dr shopping. If you ever get caught up in the system doing that you can't ever get proper help. And when you're getting"proper" help it's usually not enough.

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lenora Says:

I am diabetic,and can't take all medications. But can anyone tell me what is good for Rheumatoid Arthritis. I take oxycodone 10mg every 6 hrs, gabapentin 300mg every 6 hrs.,and TIZANICINE 4MG every 12 hrs, nothing helps. Also can you tell me which is stronger hydrocodone/Aectam10-325mg or oycycodone/acetam / 10-mg. Thanks in advance for your help.

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DR Oxy Says:

Oxycodone is stronger of the 2 but they actually act on different opioid recepters while everyone is different they can produce similar results. When it comes to RA i would suggest staying with the oxycodone but i would ask your doctor for a variant that does not have tylenol in it. This will allow higher doses to be used and you can go up by 5mg at a time up to 20mg tablets and then it jumps to 30mg tablets.

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VinnyAz Says:

A quick tool to compare the strength of opioids is available here:

I hope this helps everyone.

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