Adderall Ir Is Not Working As Well As Adderall Xr (Page 3) (Top voted first)

I recently switched from adderall xr 30mg to adderall ir 20mg because of the price of the medication. Now im in space and unproductive, moody and sleepy. WHY???

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You could be just taking too much as it is instant release instead of extended as you are used to. What I do with mine is break it in halves usually. If I take a whole one, it doesn't last all day, it is very strong at first... then once it's gone, I'm extremely edgy and mean. So I do 1/2 in the am and 1/2 between lunch and 2. It's my ghetto way of taking an extended release lol. :) And I take generic, and I like it.

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Ok I got my new new refill and i am having the same problem barr has changed the active ingrediants,i to have called and they me only the nonactive ingrediants have changed ,but they make feel in a daze all day .What are we to do ?my insurance thinks I am crazy ,but i know they are not the same.teva told me they are only going to make name brand.They you only what they want you to hear

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Please reply back if you can get ahold of any Sandoz or what not. I'm interested to see what if any difference you find...as im just stuck with Barr for the time being

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Will do.

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BTW this stuff really does help me. I just really enjoy the effect that go beyond that. I know none of you have lectured me but I am sure someone will eventually come along who will. All I can say is...Are you happy right now?

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I actually was taking Name brand XR for about 18 months and then it changed to Generic XR for about the last year I was on it. I noticed no change in effectiveness. I actually did not even realize they had switched it since the capsules were almost identical except for the imprint (ink).
I believe at that time Shire still manufactured both the generic and Adderall brand so the pills were probobly identical in composition.

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Is the adderall still working for you?

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The pink roOund pills are corepharma

I've been taking half a Barr 30 mg twice a day for a few
Months. I'm a little motivated but still low energy. I have been cutting the pills larger for a few weeks, so I've probably been taking 20 mg in am then 15 mg afternoon. I asked my dr for 20 mg pills since I'm basically mucking up the dosage by guessing where to cut the 30's. I found a place that carried the
Eon lab brand. Are these way stronger? Should I cut them in half to try?

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maybe have your dr prescribe you a mood med too and it will help with the irritated,grouchy feeling

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You say you were switched from Adderall XR 30mg to to Adderall 20mg (BTW: the "IR" designation is not needed, nor is it recognized by any professional or regulatory body--hence it is incorrect; just use Adderall to refer to the non-extended release formulation, and Adderall XR to refer to the extended release formulation), but you have not provided a dosing regimen. The maximum # of times Adderall XR should be administered in one day is usually two, preferably one. I prescribe on average 30mg of the XR to be taken at 7AM, or when first waking, followed by a second dose around noon to 2PM. That is a dose I have found most often efficacious in adult males. If I were to switch them to the non-extended release form, the I would lower the total mass of the salts to 15mg or 20mg, TID - q 8AM, noon, 4:00PM.

What you left out is critical to understanding the issue--did your physician have you on 30mg of the extended release form once or twice a day? When they switched you to Adderall 20mg, how many times a day was that prescribed to be administered?

While I have seen the phenomenon of selective response between brand vs. generic, it has never held water as tenable. To suggest that there is a difference is to spit in the face of chemistry, biology, and basic logic. Now I do know that there are differences when one make is not holding up their end of the bargain (rare), or when the delivery mechanism used in the brand is not the same as in the generic. For instance, if one maker comes up with a way to deliver medication over 12 hours and it relies on progressive dissolution of the API's (think of a tablet that under it's outer coating, has a layer of API('s), then a slow dissolving inert layer, followed by a layer of the API, etc. Now consider another maker has come up with a way to delivery medication over 12 hours, but it uses an osmotic pump or similar mechanism. In MOST people, there will be no noticeable difference, and in the eyes of the regulators, there is no difference. But for a group of individuals, for various reasons, they will notice the difference. Perhaps some have more acidic stomachs causing an increased amount of the dissolution based technology to be wiped out early on. I have seen patients who respond better to generics than to the brand (particularly with psychotropics), so to sum this up, generic doesn't mean a great deal of expense hasn't been invested (the lower cost is due to the fact that the drug (API) in question has been deemed acceptable by the FDA, and thus the generic manufacturer does not need to invest time & expense in 1) new compound discovery 2) drug trials (familiar with a drug being in say "Phase Two trials,"
3) advertising, and other factors. So, when I say that those patients who claim a difference are essentially spitting in the face of chemistry, biology, etc., I mean that there is no human who has yet been encountered who, when given "x"mg of drug "y" in the "IR" or form lacking extended/controlled release mechanisms, made by the original patent holder (brand), and then the experiment repeated with all the variables the same, except drug "y" was manufactured by generic rival, could any person thus encountered tell the difference. These are discrete compounds, your body cannot tell whether Endo made the oxycodone HCl/APAP or whether it was Roxane.

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Hi Allen- I'm just checking to see if you still need an answer to your question. Regards, Daniel

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My best guess is that your dosage is off slightly.
I have taken Immediate Release since day 1.
One thing that I've recognized in the genetics is that tweaking the dose until you get it right is a must. Trial & error is the only way to truly understand each different generic.
If I had a dollar for every time I said "placebo" or "sugar pill" or "brand x absolutely F'ing sucks."
In my experience upping and downing dosage, I was surprised even amazed at how as little as 2.5mgs or 5mgs up or down can make a HUGE difference in your Adderalls' daily performance.
Play with it. Break them in 1/2, then 1/4's so you can be more accurate with your number. It matters.

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What stands out to me about your post is you decreased your dose from 30mg down to 20mg. I'm guessing you take at least 2 20mg IR tablets per day?

The effect or potency
(as some say) of XR is also diluted somewhat...The controlled release of XR ideally releases 30mg of Adderall, over a period of many hours. (8-12)

The 20mg IR is immediately released (what %, I don't know), but it's designed release is to give me all it's active ingredient between 4-6 hours per dose for me.

Way more active ingredient in my system in a much shorter span of time equals the boost I need to solve problems better, multi-task better...you get the idea.

So...naturally you should feel different (worse for you) because you are taking different amounts of Adderall now than before & those amounts are being released at different times in your system than before.

I have no personal experience with XR.
I only use IR Adderall...and for many reasons.
Gives me control to alter my dose up or down a few milligrams which helps me stay on top of my ideal dose. And yes...my right dose changes every few weeks.
IR gives me psychological relief because when it kicks in, I feel it and then I know it's working, so I can move forward with my day.

My best guess for your situation and the symptoms you described requires only a minor adjustment in milligrams and/or frequency.
I'm no doc, so ask yours. But this has worked for me in my Adderall experience.

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Hello. I take Adderall IR (generic Sandoz) and the medication only seems to last 1 to 2 hours. I hear that XR lasts longer but it comes with more crashes or bad effects, is this true? Has anyone had the medication last a short time and then start lasting longer?

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TEVA pharmaceuticals issued a voluntary recall for certain lots of their generic Adderall IR on May 22, 2020

Citing the possibility bottles may contain tablets of mixed strengths, Teva Pharmaceuticals USA is voluntarily recalling 100-count bottles of dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets (mixed amphetamine salts product). The recall was included in the June 10, 2020, US Food and Drug Administration (FDA) Enforcement Report.

The following products, distributed throughout the United States and in Puerto Rico, were included in the recall:

5-mg dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets in 100-count bottles (NDC 0555-0971-02) from lot 42614718 (Exp. 2/21);

15-mg dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets in 100-count bottles (NDC 0555-0777-02) from lot 42617008 (Exp. 10/21);

20-mg dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfate tablets in 100-count bottles (NDC 0555-0973-02) from lot 42617891 (Exp. 1/22).

Teva Pharmaceuticals initiated the recalls May 22, 2020.

The FDA designated the recalls Class II on June 4, 2020, signaling use of the tablets could cause temporary or medically reversible adverse health consequences. A remote possibility of serious harm also exists.

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if I double my ir dose will it double the length making it last longer?

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The XR was a controlled release medication, the drug is released slowly over hours of time to keep a steady dose in your body.

The IR is instant release, so all the medication is released at once and also processed out of your body much faster.

Did you doctor approve this switch?

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You're so high off the drug you don't even realize it. Your reaction to looking all over the web for answers that you admit you will find on Monday is ridiculous. You have no reason to freak out if you're taking the prescribed dose and can't tell the difference. The fact that you are doing so is the adderall working it's wonder.

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